FDA Announces Prescription And Over-The-Counter Drugs Such As Aleve, Motrin, Advil And Celebrex, Also Know As NSAIDs, That Are Used To Treat Long- And Short-Term Medical Conditions Such As Arthritis, Joint Pain, Headaches and even Cold And Flu symptoms Can Cause Heart Attacks and Strokes.
The U.S. Food and Drug Administration (FDA) has strengthened its existing warning that nonsteroidal anti-inflammatory drugs (NSAIDs) increases the risk of heart attack and stroke, Wright & Schulte LLC reports. The federal regulatory agency said it is requiring updates to the drug labels of prescription NSAIDs, and will request updates to the drug fact labels on over-the-counter non-aspirin NSAIDs regarding the heart attack and stroke risk. Among the popular NSAID name brands are Advil, Aleve, Celebrex and Motrin which consumers use to treat everything from cold and flu to arthritis pain. NSAIDS are also sold under the generic names, including ibuprofen, naproxen sodium, and celecoxib. According to the agency, heart attack and stroke risks with NSAIDs were first placed on the warnings section of the prescription drug labels in 2005. However, the FDA said it has reviewed “a variety of new safety information” on prescription and OTC NSAIDs, including observational studies, clinical trials and other scientific publications. The FDA advise patients taking NSAIDS to seek medical attention immediately if they experience such symptoms as chest pain, shortness of breath or trouble breathing, weakness in one part or side of their body or sudden slurred speech.
[fda.gov/Drugs/DrugSafety/ucm451800.htm, July 9, 2015]
“The FDA also advises patients and health care professionals to remain alert for heart-related side effects the entire time that NSAIDs are being taken,” says Wright & Schulte LLC.
The Firm is currently investigating NSAID side-effects lawsuits. If you have suffered a heart attack or stroke due to taking NSAIDs, such as Advil, Celebrex, Motrin or Aleve, please contact Wright & Schulte LLC for a free lawsuit case evaluation by completing the form on the right side of the page or call us at 1-800-399-0795.
As stated by the FDA, NSAIDs work by blocking the production of chemicals linked to pain and inflammation called, “prostaglandins.” NSAIDs reduce pain and inflammation by blocking these chemicals. People who have cardiovascular disease, particularly those who recently had a heart attack or cardiac bypass surgery, are at the greatest risk for cardiovascular adverse events associated with NSAIDs. Heart attack or stroke risk can occur as early as the first weeks of using an NSAID and may increase with longer use and higher doses, according to the FDA. Patients treated with NSAIDs after a first heart attack were more likely to die within the first year compared to patients who were not exposed after a first heart attack. The FDA further said that the use of NSAIDs may also increase the risk of heart attack or stroke in patients with or without heart disease or risk factors for heart disease.
FDA and NSAID Studies
Among the studies reviewed by the FDA was a meta-analyses on the vascular and gastrointestinal effects of NSAIDs. The study, published in May 2013 in The Lancet, had a 33 percent higher risk of having a stroke, heart attack or early death. According to the study, ibuprofen (Advil, Motrin) significantly increased major coronary events, but not major vascular events. Vascular death was increased significantly by coxibs (Celebrex) and diclofenac (Cambia, Voltaren). The study also found that the risk of heart failure was roughly doubled by all NSAIDs, and all NSAID regimens increased upper gastrointestinal complications.
[thelancet.com/journals/lancet/article/PIIS0140-6736(13)60900-9/abstract, May 30, 2013]
A study published in the July issue of the journal, Hypertension, suggests that patients with high blood pressure who regularly take NSAIDs may increase their risk of chronic kidney disease. Researchers from the Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan, used a health insurance database to review 31,000 individuals with hypertension and found a 32 percent increased risk of kidney disease in people who took NSAIDs for at least 90 days. The results also showed that individuals who took NSAIDs for less than 90 days were at an 18 percent increased risk of developing chronic kidney disease.
[ncbi.nlm.nih.gov/pubmed/26169048, July 2015]
About Wright & Schulte LLC
Wright & Schulte LLC, an experienced personal injury firm, is dedicated to the belief that America’s legal system should work for the people. Every day, the attorneys of Wright & Schulte LLC stand up for the rights of people who have been injured or wronged and fight tirelessly to ensure that even the world’s most powerful corporations take responsibility for their actions. If you’re looking for a law firm that will guarantee the aggressive and personal representation you deserve, please do not hesitate to contact Wright & Schulte LLC today. Free NSAID lawsuit case evaluations are available through yourlegalhelp.com or by calling 1-800-399-0795.
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