Onglyza Lawsuit | Kombiglyze XR Lawsuit | Side Effects: heart failure etc.

Onglyza Lawsuit | Kombiglyze XR Lawsuit | Side Effects: heart failure, thyroid cancer, pancreatitis, and pancreatic cancer

Onglyza Lawsuits, Kombiglyze Lawsuits, Onglyza Heart Failure Lawsuit, Kombiglyze Heart Failure Lawsuit, Onglyza Side Effects Lawsuits, Kombiglyze Side Effects Lawsuits, | Onglyza DDP-4 Inhibitor Lawsuit | Kombiglyze XR DDP-4 Inhibitor Lawsuit

onglyza-heart-failure-lawsuit-lawyerOnglyza Lawsuit and Kombiglyze XR Lawsuit Information: Onglyza and Kombiglyze XR, prescription medications used to treat type 2 diabetes, have the potential to cause life-threatening side effects that include heart failure, thyroid cancer, pancreatitis, and pancreatic cancer. The drugs Onglyza and Kombiglyze XR have come under scrutiny by the U.S. Food and Drug Administration (FDA) which is currently evaluating the link between type 2 diabetes drugs like Onglyza and Kombiglyze XR and cardiovascular risks like heart failure that require hospitalization.

Study found patients who took saxagliptin ( Onglyza & Kombiglyze XR ) had a 27 percent higher risk of heart failure

In February 2014, the FDA asked AstraZeneca to investigate a potential link between saxagliptin ( Onglyza & Kombiglyze XR ) use and heart failure after reviewing a randomized controlled clinical trial. The SAVOR study found a 27 percent increase in the rate of patients who took saxagliptin and were hospitalized for heart failure compared to those who took a placebo. The study was published in October 2013 in The New England Journal of Medicine. In April 2015, the FDA’s Endocrinologic and Metabolic Drugs Advisory Committee voted 14-1 in favor of the FDA requiring saxagliptin to carry a warning label about the risk of heart failure. The one dissenting committee member voted to pull the drug from the market.
[nejm.org/doi/full/10.1056/NEJMoa1307684, NEJM, October 3, 2013]
[astrazeneca.com/our-company/media-centre/press-releases/2015/fda-advisory-committee-reviews-saxagliptin-type-2-diabetes-14042015.html, AstraZeneca, April 14, 2015]

Onglyza Lawsuit & Kombiglyze XR Lawsuits For Heart Failure Being Investigated By Wright & Schulte

The attorneys at Wright & Schulte LLC are offering free, no-obligation Onglyza Lawsuit & Kombiglyze XR Lawsuit legal reviews to individuals who were prescribed the type 2 diabetes drugs, Onglyza or Kombiglyze XR, and suffered heart failure, pancreatitis, pancreatic cancer, thyroid cancer or other serious side effects as a result of taking these medications. To speak with one of the firm’s Onglyza Lawsuit attorneys or Kombiglyze XR Lawsuit attorneys, contact Wright & Schulte for more information on this and other harmful drugs. Free Onglyza Lawsuit and Kombiglyze XR Lawsuit case evaluations are available through yourlegalhelp.com, or call 1-888-399-0795.

Onglyza side effects and Kombiglyze XR side effects can cause dangerous side effects that include:

  • Heart failure
  • Thyroid cancer
  • Pancreatitis (inflammation of the pancreas)
  • Pancreatic cancer
  • Lactic acidosis (a build up of lactic acid in the blood)

The FDA And DPP-4 Inhibitors

Saxagliptin ( Onglyza & Kombiglyze XR ) is a generic drug marketed as Onglyza and Kombiglyze XR. The FDA approved Onglyza in 2009 and Kombiglyze XR (saxagliptin and metformin hydrochloride extended-release) in 2010. The two medications belong to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. According to the FDA, DPP-4 inhibitors are used along with diet and exercise to lower blood sugar in adults with type 2 diabetes by inhibiting an enzyme in the body that reduces insulin production. In August 2015, the FDA announced that severe and disabling joint pain have been associated with DDP-4 inhibitors.
[http://www.fda.gov/Drugs/DrugSafety/ucm459579.htm, FDA, August 28, 2015]

Onglyza Side Effects and Kombiglyze XR Side Effects

In 2013, the FDA began investigating reports of pancreatic and thyroid cancers as side effects of Onglyza and other incretin mimetic drugs for type 2 diabetes. The investigation began after a review of the FDA’s adverse events database from 2004-2009 showed reports of pancreatitis, pancreatic cancer, and thyroid cancer in people who were prescribed the drugs to treat type 2 diabetes. Incretin mimetic drugs work by mimicking the incretin hormones that the body usually produces naturally to stimulate the release of insulin after a meal.

Onglyza side effects & Kombiglyze XR side effects include: